99. Members must, with respect to research subjects, ensure(1) that each subject has been informed of the project’s objectives, its benefits, risks or disadvantages relating to their participation, the benefits that would be obtained through ordinary care, if applicable, as well as the fact, as the case may be, that the members will derive a material gain from registering or keeping the subject in the research project; and
(2) that free and enlightened written consent, revocable at any time, is obtained from each subject before the beginning of participation in the research project or at the time of any material change in the research protocol.